Peptide Therapy
Common Peptides
Peptides within this group have shown remarkable efficacy in providing cells with the necessary components to recover their functionality following damage.
BPC-157
BPC-157 (Body Protection Compound-157) is a synthetic peptide consisting of 15 amino acids. It is derived from a naturally occurring protein known as Body Protection Compound (BPC) found in the human stomach. BPC-157 has been studied for its potential therapeutic effects on various conditions such as inflammation, tissue repair, and gastrointestinal disorders.
Some studies have shown that BPC-157 may promote healing of muscle, bone, and joint injuries, improve digestive function, and protect the liver from damage. It is believed to work by stimulating the production of growth factors, increasing blood flow, and reducing inflammation in the affected areas.
These peptides stimulate the release of growth hormone, which can promote muscle growth and reduce body fat.
CJC-1295
CJC-1295 is a synthetic peptide that is used as a growth hormone-releasing hormone (GHRH) analogue. It is a modified form of GHRH, designed to increase the half-life and bioavailability of the peptide in the body.
CJC-1295 works by stimulating the release of growth hormone from the pituitary gland. This peptide binds to the receptors on the pituitary gland, which triggers the release of growth hormone into the bloodstream. The increased level of growth hormone then stimulates the liver to produce insulin-like growth factor 1 (IGF-1), which has a range of health benefits.
CJC-1295 is often used by athletes and bodybuilders to enhance muscle growth, improve recovery time, and reduce body fat. It has also been studied for its potential therapeutic uses in conditions such as osteoporosis, chronic fatigue syndrome, and growth hormone deficiency.
Ipamorelin
Ipamorelin is a synthetic peptide that is similar in structure to growth hormone releasing hormone (GHRH). It works by stimulating the pituitary gland to produce more growth hormone (GH), which in turn can increase Insulin-like Growth Factor 1 (IGF-1) levels in the body.
Ipamorelin has been shown to have a selective effect on GH release, meaning that it stimulates the release of GH without affecting other hormone levels. This selective action may make it a safer and more effective alternative to other GH-releasing peptides.
Ipamorelin is commonly used in the fitness and bodybuilding communities as a performance-enhancing substance, as increased levels of GH and IGF-1 can help to promote muscle growth and recovery.
These peptides play a role in reducing chronic inflammation, which can contribute to various health conditions, such as arthritis, asthma, and cardiovascular disease.
KPV
KPV (Lys-Pro-Val) is a small peptide composed of three amino acids that has been found to have potential anti-inflammatory effects in the body. It is a naturally occurring peptide that is derived from alpha-1 antitrypsin, a protein that is involved in regulating inflammation.
Studies suggest that KPV may work by inhibiting the activity of enzymes called matrix metalloproteinases (MMPs), which are involved in the breakdown of connective tissue and play a role in the inflammatory response. By inhibiting MMP activity, KPV may help to reduce inflammation and promote tissue healing.
KPV is commonly used to support treatment of leaky gut syndrome, inflammatory bowel diseases, such as Crohn’s and ulcerative colitis, as well as skin conditions, such as psoriasis, eczema, dermatitis, ulcers, wound healing, and scar formation.
Hormone optimizing peptides are a class of peptides that can stimulate the release of hormones or modulate their activity in the body.
Kisspeptin
Kisspeptin is commonly used to support treatment plans designed to address low libido, sexual performance, infertility, and low testosterone.
Kisspeptin is important in hypothalamic regulatory circuits and directly stimulates gonadotropin-releasing hormone via G protein-coupled receptor 54. This peptide is involved in reproductive homeostasis, shown to improve endogenous testosterone, stimulates secretion of aldosterone and the release of insulin. Newly available information has connected kisspeptin with its involvement in regulating metabolism. Additionally, current findings indicate that kisspeptin might participate in controlling food consumption, maintaining glucose balance, and mediating the impact of energy levels on reproductive function.
PT-141
PT-141 is a synthetic peptide that has been developed as a treatment for sexual dysfunction in men and women, particularly those with hypoactive sexual desire disorder (HSDD) and erectile dysfunction (ED). It is a derivative of the peptide hormone melanotan II, which is known for its ability to stimulate skin pigmentation.
PT-141 works by stimulating the melanocortin receptors in the brain, which are involved in the regulation of sexual function and desire. It has been shown to increase sexual arousal, desire, and satisfaction in both men and women.
This category of peptides have been studied for their potential to improve overall health and increase longevity by targeting cellular processes related to aging. These peptides work by modulating cellular metabolism, reducing inflammation, and promoting cellular repair and regeneration.
Rapamycin
Rapamycin is a drug that was originally developed as an immunosuppressant to prevent organ rejection in transplant patients. It works by inhibiting the activity of a protein called mTOR (mammalian target of rapamycin), which plays a key role in the regulation of cell growth and division.
Rapamycin has since been found to have potential therapeutic uses in a variety of other areas, including the treatment of cancer, neurodegenerative diseases, and aging. It has been shown to have anti-inflammatory, antioxidant, and immunomodulatory effects, and may also promote autophagy (the process by which cells break down and recycle damaged or unnecessary components).
Studies suggest that rapamycin may help to slow the aging process by reducing the accumulation of cellular damage and promoting cellular repair mechanisms. It has also been shown to extend lifespan in several animal models, including mice.
Targeting metabolic pathways, particularly mitochondrial function, peptides within this group offer an effective means to enhance cellular efficiency.
Semaglutide
Semaglutide has also been studied for its potential use in weight management. In clinical trials, semaglutide has been shown to be effective in helping people with obesity lose weight. The medication works by reducing hunger and increasing feelings of fullness, which can lead to reduced calorie intake and weight loss. In addition to its effects on appetite, semaglutide may also help to improve insulin sensitivity and reduce inflammation, which are factors that can contribute to obesity and metabolic disorders. Semaglutide for weight loss is administered as a once-weekly injection and is currently approved by the U.S. Food and Drug Administration (FDA) under the brand names Wegovy and Ozempic for adults with a body mass index (BMI) of 30 or greater, or a BMI of 27 or greater with at least one weight-related condition such as high blood pressure or type 2 diabetes.
Sermorelin Acetate
KPV (Lys-Pro-Val) is a small peptide composed of three amino acids that has been found to have potential anti-inflammatory effects in the body. It is a naturally occurring peptide that is derived from alpha-1 antitrypsin, a protein that is involved in regulating inflammation.
Sermorelin is a synthetic peptide that is used to stimulate the production of human growth hormone (HGH) in the body. It is a growth hormone-releasing hormone (GHRH) analog that works by binding to the receptors in the pituitary gland, which then triggers the release of HGH.
It is administered as a subcutaneous injection and is usually given before bedtime to mimic the natural release of HGH during sleep. Sermorelin is considered a safer and more natural alternative to HGH therapy, as it promotes the body’s own production of growth hormone rather than introducing synthetic HGH into the body.
Studies suggest that KPV may work by inhibiting the activity of enzymes called matrix metalloproteinases (MMPs), which are involved in the breakdown of connective tissue and play a role in the inflammatory response. By inhibiting MMP activity, KPV may help to reduce inflammation and promote tissue healing.
KPV is commonly used to support treatment of leaky gut syndrome, inflammatory bowel diseases, such as Crohn’s and ulcerative colitis, as well as skin conditions, such as psoriasis, eczema, dermatitis, ulcers, wound healing, and scar formation.
Tirzepatide
Tirzepatide is a type of medication that belongs to a class of drugs called dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists. It is used to treat type 2 diabetes, a condition in which the body is unable to properly use insulin to regulate blood sugar levels.
Tirzepatide works by stimulating the release of insulin from the pancreas, slowing the absorption of glucose from the intestine, and reducing the production of glucose by the liver. It also reduces appetite and food intake, leading to weight loss.
Tirzepatide is typically administered via injection once per week. It has been shown to be effective at lowering blood sugar levels and promoting weight loss in people with type 2 diabetes. It may also reduce the risk of cardiovascular events in some patients.
So what are Peptides?
Peptides are molecules made up of amino acids that are linked together by peptide bonds. Amino acids are the building blocks of proteins, and peptides can be thought of as small proteins.
Peptides are found naturally in the body and play a variety of important roles, such as signaling molecules that regulate cell function and hormone production. They can also act as neurotransmitters and modulate immune function.
In medicine, synthetic peptides are used as therapeutic agents to treat a wide range of conditions, including diabetes, cancer, and autoimmune diseases. Because of their small size and specificity, peptides have advantages over larger molecules, such as proteins, and are often easier to synthesize, modify, and administer.
It’s important you speak with your Certified EvexiPEL Provider to see if your symptoms are indicative of hormone imbalance.
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